Can You Take Vitamin A and Vitamin D3 Together?

Dose or timing may matter

The short answer

High-dose vitamin A can antagonize vitamin D at the receptor level (VDR), potentially reducing vitamin D's effects on calcium metabolism.

How to arrange timing

Avoid mega-dosing vitamin A if taking vitamin D3. Standard doses of both are fine together.

Reference

Reference noted for this combination: NIH ODS 2024

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.