← Back to all supplement pairs
Can You Take Phosphatidic Acid and Vitamin C Together?
May affect absorption
The short answer
High-dose vitamin C has antioxidant effects that may blunt the reactive oxygen species (ROS) signaling required for optimal mTOR activation, potentially reducing phosphatidic acid's anabolic stimulus around training.
How to arrange timing
Avoid taking high-dose vitamin C (>500 mg) immediately before or after training when using phosphatidic acid for muscle growth.
Reference
Reference noted for this combination: Gomez-Cabrera MC et al. Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance. Am J Clin Nutr. 2008;87(1):142-149
Important context
Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.