Can You Take NMN and Resveratrol Together?

Dose or timing may matter

The short answer

NMN (nicotinamide mononucleotide) boosts NAD+ levels, while resveratrol activates SIRT1 which consumes NAD+. The combination may accelerate NAD+ turnover; without balanced dosing, this could paradoxically deplete NAD+ pools.

How to arrange timing

If combining NMN and resveratrol, ensure NMN dose is sufficient to sustain the increased NAD+ demand from SIRT1 activation.

Reference

Reference noted for this combination: Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends Cell Biol. 2014;24(8):464-471

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.