Can You Take Melatonin and Yerba Mate Extract Together?

Dose or timing may matter

The short answer

Yerba mate contains caffeine which stimulates the nervous system and counteracts melatonin's sleep-promoting effects.

How to arrange timing

Avoid taking yerba mate extract in the evening when using melatonin for sleep.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.