Can You Take Magnesium and NAC Together?

May affect absorption

The short answer

Magnesium (especially oxide form) causes loose stools, and NAC commonly causes nausea. Combined use may increase GI discomfort.

How to arrange timing

Separate by at least 2 hours. Consider magnesium bisglycinate for fewer GI effects.

Reference

Reference noted for this combination: NIH ODS — Magnesium; Examine.com — NAC side effects

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.