Can You Take L-Threonate and Magnesium Together?

Use extra care with this pair

The short answer

L-Threonate is commonly used as magnesium L-threonate (MgT) for brain magnesium delivery. Taking additional magnesium supplements alongside L-Threonate may lead to excessive magnesium intake, causing diarrhea and potentially dangerous hypermagnesemia.

How to arrange timing

If using L-Threonate (as magnesium L-threonate), reduce the dose of additional magnesium supplements to avoid exceeding 400mg total elemental magnesium daily.

Reference

Reference noted for this combination: Slutsky I, et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010;65(2):165-177.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.