Can You Take L-Arginine and Magnesium Together?

Dose or timing may matter

The short answer

L-Arginine produces nitric oxide for vasodilation while magnesium is a direct vasodilator and smooth muscle relaxant. Combining high doses of both may cause excessive blood pressure lowering.

How to arrange timing

Generally safe at standard doses. Monitor blood pressure if taking therapeutic amounts of both.

Reference

Reference noted for this combination: Bode-Böger SM et al. L-arginine-induced vasodilation in healthy humans. Biochem Biophys Res Commun. 1998;244(1):234-238

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.