Can You Take L-Arginine and Licorice Root Together?

Dose or timing may matter

The short answer

L-Arginine lowers blood pressure via nitric oxide production while licorice root raises blood pressure through cortisol elevation and sodium retention. The opposing effects may cancel each other's cardiovascular impact.

How to arrange timing

Research suggests these may counteract each other's BP effects. Consider your intended cardiovascular goal before combining.

Reference

Reference noted for this combination: Sigurjónsdóttir HA et al. Liquorice-induced rise in blood pressure. J Hum Hypertens. 2001;15(8):549-552

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.