Can You Take Iron and L-Glutathione Together?

Dose or timing may matter

The short answer

Glutathione binds iron in the labile iron pool, potentially affecting iron-dependent enzymatic reactions. Additionally, iron-glutathione interactions can generate reactive oxygen species via Fenton chemistry, counteracting glutathione's antioxidant purpose.

How to arrange timing

Separate iron and glutathione supplementation; avoid taking them together, especially at high doses.

Reference

Reference noted for this combination: Hider RC, Kong XL. Glutathione: a key component of the cytoplasmic labile iron pool. Biometals. 2011;24(6):1179-1187

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.