Can You Take Guarana and L-Arginine Together?

Dose or timing may matter

The short answer

Guarana contains caffeine and raises blood pressure via sympathetic stimulation, while L-Arginine lowers BP via nitric oxide. The opposing effects may reduce the efficacy of each.

How to arrange timing

Consider separating intake times if using L-Arginine for cardiovascular benefit.

Reference

Reference noted for this combination: Moustakas D et al. Guarana provides additional stimulation over caffeine alone. Nutrients. 2015;7(5):3684-3697

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.