Can You Take Grape Seed Extract and Magnesium Together?

Dose or timing may matter

The short answer

Grape seed extract and magnesium both lower blood pressure through vasodilatory mechanisms. The combination may produce additive hypotensive effects.

How to arrange timing

Generally safe at standard doses. Monitor blood pressure if using both at therapeutic levels.

Reference

Reference noted for this combination: Feringa HH et al. The effect of grape seed extract on cardiovascular risk markers. J Am Diet Assoc. 2011;111(8):1173-1181

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.