Can You Take Glycine Propionyl-L-Carnitine and L-Carnitine Together?

Use extra care with this pair

The short answer

Glycine Propionyl-L-Carnitine (GPLC) is a modified form of L-Carnitine. Combining with additional L-Carnitine may lead to excessive total carnitine intake, increasing gastrointestinal side effects and TMAO production.

How to arrange timing

Choose either GPLC or L-Carnitine rather than combining both to avoid excessive carnitine intake.

Reference

Reference noted for this combination: Bloomer RJ, et al. Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects. Int J Vitam Nutr Res. 2009;79(3):131-141.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.