Can You Take Fish Oil (Omega-3) and Pomegranate Seed Oil Together?

May affect absorption

The short answer

Pomegranate Seed Oil (punicic acid) and Fish Oil are both polyunsaturated fatty acid supplements that compete for intestinal micelle formation and absorption. Co-ingestion may reduce the bioavailability of both.

How to arrange timing

Separate Pomegranate Seed Oil and Fish Oil by at least 2 hours for optimal absorption.

Reference

Reference noted for this combination: Mu H, Høy CE, Progress in Lipid Research, 2004; Polyunsaturated fatty acid absorption competition

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.