Can You Take Fish Oil (Omega-3) and GLA Together?

Use extra care with this pair

The short answer

GLA has antiplatelet properties via prostaglandin E1 pathway, while Fish Oil's EPA/DHA inhibit platelet aggregation via thromboxane A3 pathway. Stacking both amplifies blood-thinning effects through complementary fatty acid mechanisms.

How to arrange timing

Monitor for signs of increased bleeding when combining GLA with Fish Oil. Both affect platelet function through different prostaglandin pathways.

Reference

Reference noted for this combination: Barham JB et al., American Journal of Clinical Nutrition, 2000; GLA and EPA effects on eicosanoid production

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.