Can You Take Ellagic Acid and Iron Together?

May affect absorption

The short answer

Ellagic Acid is a polyphenol with strong iron-chelating properties. Its four hydroxyl groups and two lactone groups create a potent iron-binding structure that significantly reduces non-heme iron absorption.

How to arrange timing

Separate Ellagic Acid and iron supplements by at least 2 hours. Ellagic acid is a potent iron chelator.

Reference

Reference noted for this combination: Larrosa M, et al. Polyphenol metabolites from colonic microbiota exert anti-inflammatory activity. Eur J Nutr. 2009;48(7):380-390.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.