Can You Take Creatine and Vitamin D3 Together?

Dose or timing may matter

The short answer

Vitamin D3 promotes calcium absorption which can lead to hypercalciuria, while creatine adds creatinine clearance burden. Combined, they may increase renal workload and kidney stone risk.

How to arrange timing

Keep vitamin D3 at standard doses, maintain hydration above 3 L/day, and monitor calcium and creatinine levels periodically.

Reference

Reference noted for this combination: Gallagher JC et al. Ann Intern Med. 2014;160(1):11-17; Kreider RB et al. J Int Soc Sports Nutr. 2017;14:18

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.