Can You Take Creatine and Sustamine (L-Alanyl-L-Glutamine) Together?

May affect absorption

The short answer

Sustamine (L-alanyl-L-glutamine) enhances fluid and electrolyte absorption while creatine promotes muscle water uptake. While complementary for hydration, the combined water retention may cause temporary bloating.

How to arrange timing

A generally beneficial combination for exercise performance. Ensure adequate overall hydration and be aware of temporary water weight gain.

Reference

Reference noted for this combination: Harris RC et al. L-glutamine absorption is enhanced after ingestion of L-alanylglutamine compared with the free amino acid or wheat protein. Nutr Res. 2012;32(4):272-277

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.