Can You Take Creatine and HMB Together?

Use extra care with this pair

The short answer

Both HMB (beta-hydroxy beta-methylbutyrate) and creatine independently increase lean mass and strength. While often stacked in sports nutrition, the combined anabolic effect may increase water retention and renal metabolite clearance demands.

How to arrange timing

Ensure adequate hydration when combining HMB and creatine. Research supports the combination but monitor fluid intake and kidney markers.

Reference

Reference noted for this combination: Wilson JM, et al. International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB). J Int Soc Sports Nutr. 2013;10(1):6.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.