Can You Take CoQ10 and MitoQ Together?

Use extra care with this pair

The short answer

MitoQ is a mitochondria-targeted derivative of CoQ10 (ubiquinone conjugated to a triphenylphosphonium cation). Combining MitoQ with CoQ10 creates redundant mitochondrial antioxidant coverage and may excessively suppress mitochondrial ROS signaling.

How to arrange timing

Avoid combining MitoQ and CoQ10 — MitoQ is already a targeted form of CoQ10. Choose one based on your specific needs.

Reference

Reference noted for this combination: Smith RA, Murphy MP. Animal and human studies with the mitochondria-targeted antioxidant MitoQ. Ann N Y Acad Sci. 2010;1201:96-103.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.