Can You Take Copper and Vitamin B6 Together?

Dose or timing may matter

The short answer

High-dose vitamin B6 (pyridoxine) may chelate copper ions due to pyridoxal's affinity for divalent metals, potentially reducing copper availability in enzymatic reactions.

How to arrange timing

If taking high-dose B6, monitor copper status and consider copper supplementation if needed.

Reference

Reference noted for this combination: Klevay LM. Lack of a recommended dietary allowance for copper may be hazardous to your health. J Am Coll Nutr. 1998;17(4):322-326

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.