Can You Take Copper and Quercetin Together?

Dose or timing may matter

The short answer

Quercetin chelates copper ions through its catechol groups, forming quercetin-copper complexes. While this can have pro-oxidant effects, it may also reduce copper availability for essential cuproenzymes like ceruloplasmin and superoxide dismutase.

How to arrange timing

If taking both, separate them by at least 2 hours to minimize copper chelation.

Reference

Reference noted for this combination: Leopoldini M et al. The molecular basis of working mechanism of natural polyphenolic antioxidants. Food Chem. 2011;125(2):288-306

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.