Can You Take Collagen and Fungal Enzymes Together?

May affect absorption

The short answer

Fungal enzyme blends often contain proteases that can degrade collagen supplements in the digestive tract, potentially reducing their bioavailability as intact peptides.

How to arrange timing

Take collagen supplements at least 1 hour apart from fungal enzyme blends.

Reference

Reference noted for this combination: Rao MB, et al. Molecular and biotechnological aspects of microbial proteases. Microbiol Mol Biol Rev. 1998;62(3):597-635.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.