Can You Take CLA and Omega-9 Together?

Dose or timing may matter

The short answer

CLA may reduce the body's utilization of oleic acid (Omega-9) by competing for the same fatty acid metabolic enzymes (delta-9-desaturase). This can partially counteract the cardiovascular benefits of Omega-9 supplementation.

How to arrange timing

If taking CLA for body composition and Omega-9 for cardiovascular health, consider taking them at different times of day.

Reference

Reference noted for this combination: Banni S et al., Journal of Nutritional Biochemistry, 2004; CLA effects on lipid metabolism and desaturase activity

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.