Can You Take CLA and Fish Oil (Omega-3) Together?

May affect absorption

The short answer

CLA and Fish Oil are both lipid supplements that compete for intestinal absorption via micelle formation. Co-ingestion may reduce the bioavailability of both due to competition for lipid transport pathways.

How to arrange timing

Separate CLA and Fish Oil by at least 2 hours for optimal absorption of both fatty acid supplements.

Reference

Reference noted for this combination: Plourde M et al., Applied Physiology, Nutrition, and Metabolism, 2007; Fatty acid competition for absorption

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.