Can You Take Citrulline and Magnesium Together?

Dose or timing may matter

The short answer

Citrulline increases nitric oxide-mediated vasodilation while magnesium is a natural vasodilator and smooth muscle relaxant. Combined use may produce additive hypotensive effects.

How to arrange timing

Generally well-tolerated in healthy individuals, but monitor blood pressure if taking therapeutic doses of both.

Reference

Reference noted for this combination: Kass L et al. Effect of magnesium supplementation on blood pressure: a meta-analysis. Eur J Clin Nutr. 2012;66(4):411-418

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.