Can You Take Cat's Claw and Creatine Together?

Dose or timing may matter

The short answer

Cat's claw contains oxindole alkaloids that are renally processed. Combined with creatine's creatinine clearance burden, the kidney faces multiple metabolite clearance demands simultaneously.

How to arrange timing

Use recommended doses of both and maintain adequate hydration. Space intake if possible.

Reference

Reference noted for this combination: Heitzman ME et al. Phytochemistry. 2005;66(1):5-29; Kreider RB et al. J Int Soc Sports Nutr. 2017;14:18

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.