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Can You Take L-Carnosine and L-Histidine Together?
May affect absorption
The short answer
L-Carnosine is a dipeptide of beta-alanine and L-Histidine. Both compete for intestinal peptide/amino acid transporters, and exogenous histidine may interfere with carnosine's intact absorption via PepT1.
How to arrange timing
Separate L-Carnosine and L-Histidine by at least 1 hour to avoid transporter competition.
Reference
Reference noted for this combination: Boldyrev AA, et al. Carnosine and related compounds in biological tissues. Comp Biochem Physiol B Biochem Mol Biol. 2013;164(4):196-203.
Important context
Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.