Can You Take Calcium and Whey Protein Together?

Dose or timing may matter

The short answer

Whey protein increases renal urea nitrogen load, while calcium supplements raise urinary calcium. Both increase renal excretory demands, potentially elevating kidney stone risk.

How to arrange timing

Stay well-hydrated (2.5+ L/day). Those with a history of kidney stones should be especially cautious with this combination.

Reference

Reference noted for this combination: Curhan GC et al. N Engl J Med. 1993;328(12):833-838; Martin WF et al. Nutr Metab. 2005;2:25

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.