Can You Take Calcium and Vitamin K2 Together?

Dose or timing may matter

The short answer

High calcium intake without adequate vitamin K2 may lead to calcium deposition in arteries rather than bones. Vitamin K2 activates matrix Gla protein, which directs calcium to bone tissue; insufficient K2 antagonizes proper calcium utilization.

How to arrange timing

When supplementing calcium, consider co-supplementing vitamin K2 (MK-7) to ensure proper calcium distribution.

Reference

Reference noted for this combination: Schurgers LJ et al. The role of vitamin K and vitamin K-dependent proteins in vascular calcification. Z Kardiol. 2001;90 Suppl 3:57-63

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.