Can You Take Calcium and Vitamin D2 Together?

Dose or timing may matter

The short answer

Vitamin D2 (ergocalciferol) increases intestinal calcium absorption. While this is generally beneficial, high-dose vitamin D2 combined with high calcium supplementation may lead to hypercalcemia and increase the risk of calcium-related adverse effects.

How to arrange timing

Monitor calcium levels when taking high-dose vitamin D2 with calcium. Ensure adequate vitamin K2 intake for proper calcium distribution.

Reference

Reference noted for this combination: Hathcock JN et al. Risk assessment for vitamin D. Am J Clin Nutr. 2007;85(1):6-18

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.