Can You Take Calcium and Phytase Together?

May affect absorption

The short answer

Phytase breaks down phytic acid which normally binds calcium and reduces its absorption. While phytase may ultimately enhance calcium bioavailability, the enzymatic process alters the mineral absorption environment.

How to arrange timing

Phytase may help calcium absorption by breaking down phytate. Consider taking phytase with calcium-rich meals for best results.

Reference

Reference noted for this combination: Sandberg AS, et al. The effect of food processing on phytate hydrolysis and availability of iron and zinc. Adv Exp Med Biol. 1991;289:499-508.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.