Can You Take Calcium and Creatine Together?

Dose or timing may matter

The short answer

Both calcium and creatine increase renal workload. High-dose calcium raises urinary calcium (hypercalciuria), while creatine elevates creatinine levels, together stacking the kidney's filtration burden.

How to arrange timing

Consider spacing intake by 4+ hours and maintaining adequate hydration (2.5+ L/day). Monitor kidney function if using both long-term.

Reference

Reference noted for this combination: Poortmans JR, Francaux M. J Int Soc Sports Nutr. 2000; Curhan GC et al. N Engl J Med. 1993;328(12):833-838

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.