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Can You Take Caffeine and Thiamine Mononitrate Together?
May affect absorption
The short answer
Caffeine may increase the excretion of thiamine via diuresis and reduce its absorption. Thiamine mononitrate is a stable salt form of vitamin B1, but once absorbed it is subject to the same caffeine-enhanced urinary losses as other thiamine forms.
How to arrange timing
Space thiamine mononitrate and caffeine at least 1-2 hours apart.
Reference
Reference noted for this combination: Lonsdale D. Evid Based Complement Alternat Med. 2006;3(1):49-59; Examine.com
Important context
Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.