Can You Take Caffeine and Creatine Together?

Dose or timing may matter

The short answer

Caffeine may partially counteract creatine's ergogenic effects by opposing muscle relaxation time and intracellular water retention.

How to arrange timing

Some research suggests separating them, but the interaction is modest. Consider taking creatine away from your caffeine window.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.