Can You Take Caffeine and Creatine Nitrate Together?

Dose or timing may matter

The short answer

Caffeine may counteract creatine nitrate's dual-action ergogenic effects: it opposes creatine's muscle hydration benefits, and its vasoconstrictive tendency may reduce the nitrate component's vasodilatory action.

How to arrange timing

Consider taking creatine nitrate at a different time from caffeine to maximize both the creatine and nitrate benefits.

Reference

Reference noted for this combination: Joy JM et al. 28 days of creatine nitrate supplementation is apparently safe in healthy individuals. J Int Soc Sports Nutr. 2014;11(1):60

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.