Can You Take Caffeine and Creatine Magnesium Chelate Together?

Dose or timing may matter

The short answer

Caffeine may reduce the ergogenic benefit of creatine magnesium chelate by opposing creatine's effects on muscle relaxation and water retention. The chelated magnesium component may also be affected by caffeine's diuretic tendency.

How to arrange timing

Separate intake by 2–3 hours for optimal creatine and magnesium absorption.

Reference

Reference noted for this combination: Vandenberghe K et al. Caffeine counteracts the ergogenic action of muscle creatine loading. J Appl Physiol. 1996;80(2):452-457

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.