Can You Take Caffeine and CoQ10 Together?

Dose or timing may matter

The short answer

Caffeine temporarily raises blood pressure while CoQ10 has blood pressure-lowering properties. The opposing effects may reduce the cardiovascular benefit of CoQ10.

How to arrange timing

Consider separating intake if taking CoQ10 for blood pressure management. Research suggests caffeine may counteract CoQ10's BP-lowering effect.

Reference

Reference noted for this combination: Rosenfeldt FL et al. Coenzyme Q10 in the treatment of hypertension: a meta-analysis. J Hum Hypertens. 2007;21(4):297-306

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.