Can You Take Brain Octane (C8 MCT) and Fish Oil (Omega-3) Together?

Dose or timing may matter

The short answer

Brain Octane (C8 MCT oil) and Fish Oil are both lipid supplements. Taking high doses of both together can cause gastrointestinal distress, including nausea, diarrhea, and cramping, due to high fat load.

How to arrange timing

Separate Brain Octane and Fish Oil by at least 2 hours, or take one in the morning and the other with a later meal to reduce GI burden.

Reference

Reference noted for this combination: St-Onge MP, Jones PJ. Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity. J Nutr. 2002;132(3):329-332.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.