Can You Take Alpha-GPC and Phosphatidylserine Together?

May affect absorption

The short answer

Both support cholinergic function. Combining may cause headaches from excess acetylcholine in sensitive individuals.

How to arrange timing

Start with lower doses of each if combining.

Reference

Reference noted for this combination: Examine.com 2024

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.