Can You Take L-Tyrosine and 5-HTP Together?

May affect absorption

The short answer

L-Tyrosine (dopamine precursor) and 5-HTP (serotonin precursor) compete for the same enzyme (AADC). Taking together may reduce effectiveness of both.

How to arrange timing

Take L-Tyrosine in the morning and 5-HTP in the evening.

Reference

Reference noted for this combination: Examine.com 2024

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.