Can You Take 5-HTP and Caffeine Together?

Dose or timing may matter

The short answer

5-HTP promotes serotonin production and calmness, while caffeine stimulates the nervous system. They can partially counteract each other.

How to arrange timing

Take caffeine in the morning and 5-HTP in the evening.

Reference

Reference noted for this combination: Examine.com

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.