← Back to food and supplement guidance
Does Soy foods Affect Manganese?
May affect absorption or how you feel
The short answer
Phytic acid in soy binds divalent cations including manganese, reducing its absorption by 20-40%.
How to arrange timing
Separate manganese supplements from soy products by at least 2 hours.
Reference
Reference noted for this food and supplement combination: NIH ODS 2024; Sandström et al., J Nutr 1987
Important context
The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.