Does Grapefruit Affect Turmeric / Curcumin?

Amount or timing may matter

The short answer

Grapefruit's CYP3A4 inhibition may alter curcumin metabolism and increase bioavailability unpredictably.

How to arrange timing

Separate turmeric from grapefruit by at least 4 hours.

Reference

Reference noted for this food and supplement combination: FDA

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.