Does Alcohol Affect Kudzu Root?

Amount or timing may matter

The short answer

Kudzu inhibits aldehyde dehydrogenase (ALDH2), slowing acetaldehyde breakdown. This may increase hangover severity and acetaldehyde toxicity.

How to arrange timing

Be cautious combining kudzu with alcohol; it may intensify flushing and nausea.

Reference

Reference noted for this food and supplement combination: NIH NCCIH 2024

Important context

The effect can also change with food amount, supplement dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.