Can You Take Theobromine and Valerian Root Together?

Dose or timing may matter

The short answer

Theobromine's mild stimulant effects may reduce valerian's sedative efficacy.

How to arrange timing

Separate intake by 2-3 hours.

Reference

Reference noted for this combination: Baggott et al., 2013, Psychopharmacology

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.