Can You Take Potassium and Vitamin B12 Together?

Dose or timing may matter

The short answer

Potassium supplements (especially potassium chloride) may reduce vitamin B12 absorption by decreasing ileal pH and impairing intrinsic factor-mediated B12 uptake in the terminal ileum.

How to arrange timing

If taking potassium supplements long-term, monitor B12 levels periodically.

Reference

Reference noted for this combination: Russell RM et al. Vitamin B12 deficiency associated with potassium supplements. Ann Intern Med. 1988;108(5):739

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.