Can You Take Melatonin and Passionflower Together?

Use extra care with this pair

The short answer

Melatonin and passionflower act through different but complementary sedative pathways; combined use may cause excessive drowsiness.

How to arrange timing

If combining for sleep, reduce doses of each.

Reference

Reference noted for this combination: Ngan & Conduit, 2011, Phytother Res

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.