Can You Take Lemon Balm and Melatonin Together?

Use extra care with this pair

The short answer

Lemon balm inhibits GABA transaminase while melatonin acts on MT1/MT2 receptors; combined sedation may be excessive.

How to arrange timing

Reduce doses if combining for sleep support.

Reference

Reference noted for this combination: Cases et al., 2011, Nutrients

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.