Can You Take Lactoferrin and Lysozyme Together?

Dose or timing may matter

The short answer

Lysozyme has enzymatic activity that can degrade glycoproteins. Lactoferrin is a glycoprotein, and lysozyme may partially degrade it in the digestive tract, reducing its bioavailability.

How to arrange timing

Take Lactoferrin at least 1 hour apart from Lysozyme supplements to preserve lactoferrin's integrity.

Reference

Reference noted for this combination: Lonnerdal B. Nutritional and physiologic significance of human milk proteins. Am J Clin Nutr. 2003;77(6):1537S-1543S.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.