Can You Take L-Alanine and L-Glutamine Together?

May affect absorption

The short answer

L-Alanine and L-Glutamine share overlapping intestinal amino acid transporters (System ASC and System N). High doses of either may competitively reduce absorption of the other.

How to arrange timing

Separate L-Alanine and L-Glutamine by at least 1 hour for optimal absorption of both amino acids.

Reference

Reference noted for this combination: Bröer S. Amino acid transport across mammalian intestinal and renal epithelia. Physiol Rev. 2008;88(1):249-286.

Important context

Whether supplements suit you together also depends on dose, product formulation, health conditions, and medication use. Ask a doctor or pharmacist first if you take medication, are pregnant or breastfeeding, or have a chronic condition.